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Scientist

Synectics Inc
locationCambridge, MA, USA
PublishedPublished: 6/14/2022
Science
Full Time

Job Description

Job Description

Responsibilities:

  • Seeking a highly motivated and experienced scientist with cell and molecular biology laboratory experience to join the CRISPR Center of Excellence, working collaboratively with FIIT teams to advance the immunology pipeline.

  • Independently performs cellular and molecular biology laboratory procedures, including immune cell culture, cellular functional assays, lentivirus generation, transfection, electroporation, and single cell cloning, nucleic acid and protein extraction, isolation, and purification, DNA sequencing, PCR, qRT-PCR, Western blot

  • Support small molecule and biologics drug development

  • Support target biology validation using genetic tools, including gene overexpression via ORF; CRISPR-based technologies; RNAi; mutagenesis; validation of genetic manipulations.

  • Maintain accurate laboratory records and data.

  • Maintain expert proficiency in laboratory techniques and passionately learn additional workflows in support of new projects and adjacent teams

Qualifications:

  • Bachelor's or Master's degree in molecular biology, immunology or other biological sciences with 2+ years (MS) or 3+(Bs) hands-on experience

  • Skillful in cellular and molecular biology techniques, such as mammalian cell culture, lentivirus production, PCR, and gel electrophoresis; experience in genomic DNA isolation and validation of genomic edits

  • Experience with a wide range of cell-based assays

  • Solid understanding of genetic tools such as CRISPR and RNAi-based technologies

  • Prior industry experience

  • Good communication, both speech and writing, to a variety of audiences

  • Ability to collaborate with peers and their teams

  • Prefer experience with functional CRISPR screening

  • Experience in small molecule drug development and screening desired

  • Hands-on experience with immunoassays including cell culture, FACS, ELISA, WB is preferred

  • Bioinformatics experience is a plus

  • Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance

  • Learns fast, grasps the "essence" and can change course quickly where indicated

  • Raises the bar and is never satisfied with the status quo

  • Creates a learning environment, open to suggestions and experimentation for improvement

  • Embraces the ideas of others and nurtures innovation to make possibilities real

  • This position requires passion, attention to detail, prior hands-on experience, and teamwork.

Benefits:

Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.

Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.

Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.

Technical Certification Bonus: Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.

Synectics is an equal opportunity employer.

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