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city

state

<h3>Job Description</h3>
Job Description
Job description:
<ul>
<li>
We are currently seeking a highly motivated and passionate scientist to join our team in Immunology Discovery based in Cambridge MA.
</li>
<li>
In this role, the candidate will collaborate with multiple cross-functional teams to advance portfolio projects, with a particular emphasis on supporting in vitro data generation. 
</li>
<li>
Responsibilities include performing and adapting cell-based in vitro protocols in a timely manner across diverse cell systems, data analysis and effective communication of results, and collaboration across multiple teams. 
</li>
<li>
The position offers a unique opportunity for a talented scientist to work in a dynamic, innovative, and multi-disciplinary environment to develop their career at the interface of basic research and early drug discovery. 
</li>
<li>
The position requires ability to work independently, demonstrate excellent technical, written and oral communication skills and work very well in a collaborative team environment.
</li>
<li>
Human colon organoid culture, passaging, and plating for experiments to support the group
</li>
<li>
Perform cell-based assays using cell lines and mammalian primary cells
</li>
<li>
Test biologic and small molecules in cell-based assays for functional readouts including cell proliferation, cytokine release, and gene expression.
</li>
<li>
Perform advanced molecular and cellular biology techniques (including but not limited to FACS, ELISA, MSD, HTRF, qPCR)
</li>
<li>
Responsibilities may include processing animal tissue ex vivo and isolation of immune cells from human and animal tissue or blood
</li>
<li>
Work independently on the design, execution and interpretation of experimental results to validate hypotheses related to the project need
</li>
<li>
Maintain close communication with multiple groups to support human colon organoid cell needs
</li>
<li>
Implement and innovate new experimental protocols/techniques as needed
</li>
<li>
Analyze, interpret, document and report data consistently, concisely and rigorously, both to individual stakeholders and in group settings
</li>
<li>
Demonstrate scientific excellence through dedication to multiple projects in a fast-paced multi-disciplinary environment
</li>
<li>
Impact projects mostly through lab-based activities
</li>
</ul>
Qualifications 
<ul>
<li>
Must have a bachelor's degree in Biological Science or related field with 2+ years of experience in biotech or pharma setting (industry experience)
</li>
<li>
Experience in in vitro cell culture (sterile techniques, handling challenging cell types) is required.
</li>
<li>
Experience with primary epithelial cells and human colon organoids is required.
</li>
<li>
Experience with immune cells including myeloid cells (monocytes macrophages or dendritic cells) is required.
</li>
<li>
Experience in immunoassays including multi-color flow cytometry and ELISA (or MSD, HTRF) is required.
</li>
<li>
Experience with gene expression analysis by qPCR is required
</li>
<li>
Experience with ex vivo animal tissue processing is a plus.
</li>
<li>
Ability to learn new skills and apply them in a fast-paced research environment.
</li>
<li>
Creativity, problem-solving, and attention to details.
</li>
<li>
Excellent oral and written communication and collaboration skills.
</li>
<li>
Ability to work independently as well as in a team.
</li>
<li>
Proven flexibility to deal with changing timelines and shifting work priorities.
</li>
<li>
Experience with in vitro assays with primary human immune cells (ie myeloid, PBMCs)
</li>
<li>
Experience with molecular and cellular analysis techniques including qPCR, MSD, ELISA, flow cytometry
</li>
<li>
Experience with cell-based assay development is a plus.
</li>
</ul>
Benefits:
Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics. 
Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. 
Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.
Technical Certification Bonus: Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.
Synectics is an equal opportunity employer.

Biologist

<h3>Job Description</h3>
工作地点：连云港
岗位职责：
1.负责分析方法的开发和验证，包含但不限于原料药、中间体、起始物料及制剂等中的杂质分析方法的开发及验证，并进行研究方案和报告的撰写；
2.负责各项目研究过程中，遇到的疑难分析问题的解决，比如结构类似物分析方法开发，大极性化合物分析方法开发，复杂基质前处理方法开发等等；
3.负责其他分析相关攻坚问题的解决；
4.能熟练掌握不同类型分析仪器原理、操作，运用多种联用技术解决分析问题；
5.负责仪器的日常维护与保养。
任职要求：
1.博士及以上药学、分析化学、物理化学等相关专业；
2.独立开发过多个体系的色谱方法，包括小分子化药和多肽类，有有机化学和药物降解化学研究基础者优先，有手性异构体分析分离经验或多肽消旋肽研究经验者优先，有丰富的样品前处理和制备样品后处理经验者优先；
3.具有合规合作意识，具备良好的沟通能力，能吃苦耐劳，工作积极主动。
 
Job Responsibilities:
1.Lead the development and validation of analytical methods, including (but not limited to) impurity profiling methods for APIs, intermediates, starting materials, and drug products; author related study protocols and reports.
2.Resolve complex analytical challenges during project execution, e.g.:Method development for structural analogs、Analysis of highly polar compounds、Sample preparation in complex matrices
3.Address critical analytical issues requiring advanced technical expertise.
4.Demonstrate mastery of analytical instrumentation principles, operations, and hyphenated techniques (e.g., LC-MS, GC-MS) to solve analytical problems.
5.Perform routine instrument maintenance and calibration.
Qualifications:
1.Ph.D. in Pharmaceutical Sciences, Analytical Chemistry, Physical Chemistry, or related disciplines.
2.Proven experience in developing chromatographic methods for diverse systems (small molecules/peptides). Preferred candidates will have:Background in organic chemistry/drug degradation chemistry、Experience with chiral isomer separation or peptide racemization studies、Expertise in complex sample preparation/post-treatment
3.Strong GMP compliance mindset, excellent communication skills, resilience to demanding workloads, and proactive problem-solving attitude.

质量科学家 -- 恒瑞-全球精英计划

<h3>Job Description</h3>
Location:&nbsp;Woburn, MA
 
Vaxess is developing next generation medicines on our novel microneedle array patch (MAP) platform. The platform combines high temperature stability with simple self-application and only a five-minute wear time to dramatically alter the way that drugs are delivered. We are committed to enabling products that are not only more effective, but also more accessible to patients around the world. 
 
Research &amp; development at Vaxess is cross-disciplinary, integrating science and engineering across biology, chemistry, materials, and mechanics to address important unmet medical needs in biologics delivery. We are seeking a talented, collaborative, and highly motivated individual with a background in formulation and materials characterization to join our core team of scientists and engineers. This is a unique opportunity to be part of an emerging startup bringing innovative technology to the global market. 
 
Responsibilities 
<ul>
<li>Design and execute studies to identify novel candidates for development on the MAP platform, build platform flexibility and utility to support pipeline product development. </li>
<li>Develop platform and product formulations enabling room-temperature distribution and storage of MAPs. </li>
<li>Serve as subject matter expert and lead on materials characterization for the Platform Research team.</li>
<li>Document and analyze experimental results, effectively communicate research results through technical presentations and written reports. </li>
<li>Develop and document test methods to characterize MAP formulations and functional device performance.</li>
<li>Collaborate closely with analytical, MAP manufacturing, and preclinical colleagues to generate proof of concept with new molecules, materials; support early collaborations with strategic partners. </li>
<li>Provide technical guidance to and mentor junior scientists/engineers as needed. </li>
<li>Contribute to intellectual property filings and regulatory submissions. </li>
</ul>
 
Qualifications 
<ul>
<li>PhD in Biological/Chemical Engineering, Materials Science, Chemistry, or related discipline with at least 2 years of relevant experience; or BS/MS with at least 7 years of relevant experience. </li>
<li>Experience with development of protein/peptide formulations and materials characterization in the context of polymer drug delivery platforms is ideal. </li>
<li>Experience with physical properties characterization of liquid formulations and solid phase matrices (e.g. surface tension, viscosity, mechanical strength) is preferred. </li>
<li>Experience with analytical characterization of materials related to structure and moisture (e.g. spectroscopic, thermal analysis methods) is preferred. </li>
<li>Experience with GxP and familiarity with regulatory guidelines is a plus.</li>
<li>Strong attention to detail, with excellent verbal and written communication skills. </li>
<li>Demonstrated abilities to learn new skills and fields, solve challenging technical problems, think independently, and work collaboratively in cross-functional teams. </li>
<li>Entrepreneurial spirit and drive to positively impact public health. </li>
</ul>
 
Vaxess, a venture-backed biotech company, is building a team of exceptional people to rapidly advance products on its microneedle array patch platform. We work closely as a team and thrive in a dynamic, exciting, and engaging work environment. If you’re interested in joining the Vaxess team, please submit your CV/resume to <a href="mailto:careers@vaxess.com" target="_blank">careers@vaxess.com</a>.&nbsp;

Scientist/Senior Engineer I, Platform Research

<h3>Job Description</h3>
Chief Scientific Officer (CSO)
Location: Boston, Massachusetts
Company Type: Early-stage Biotech | Focus: Genetic &amp; Rare Diseases
 
About the Company:
Our client is a pioneering biotechnology company advancing transformative therapies for patients living with serious genetic and rare diseases. Backed by strong investors and a passionate leadership team, the company is translating cutting-edge science into life-changing treatments. With a robust pipeline of preclinical and early clinical programs, they are poised for rapid growth and seeking a visionary Chief Scientific Officer (CSO) to guide the scientific and strategic direction of the business.
 
Role Overview:
The CSO will be the scientific leader of the company—responsible for shaping and executing the R&amp;D strategy, driving discovery and translational programs, and building a high-performing scientific organization. This individual will work closely with the CEO, Board, and cross-functional leaders to advance novel therapies from concept through development, while ensuring scientific excellence and innovation remain at the heart of the company.
 
Key Responsibilities:
<ul>
<li>Define and lead the scientific vision and R&amp;D strategy across genetic and rare disease programs.</li>
<li>Oversee discovery, translational research, and preclinical development activities.</li>
<li>Provide strategic input into clinical development planning and regulatory interactions.</li>
<li>Build, mentor, and inspire a world-class scientific team with a culture of curiosity, collaboration, and excellence.</li>
<li>Evaluate emerging technologies, partnerships, and in-licensing opportunities to strengthen the pipeline.</li>
<li>Represent the company’s science externally — with investors, partners, and the broader scientific community.</li>
<li>Partner closely with the CEO and executive team to guide strategic decision-making and corporate growth.</li>
</ul>
 
Qualifications &amp; Experience:
<ul>
<li>PhD, MD, or MD/PhD in Molecular Biology, Genetics, or related discipline.</li>
<li>15+ years’ experience in biotech or pharma, with a strong track record of leading discovery and early development programs in genetic or rare diseases.</li>
<li>Proven ability to translate scientific innovation into therapeutic programs and move assets through IND-enabling and early clinical stages.</li>
<li>Demonstrated leadership in building and scaling R&amp;D organizations.</li>
<li>Strong understanding of gene therapy, RNA-based therapeutics, or precision medicine approaches.</li>
<li>Excellent communication, leadership, and strategic thinking skills.</li>
</ul>
 
What’s on Offer:
<ul>
<li>Opportunity to shape the direction of a cutting-edge biotech at an inflection point of growth.</li>
<li>Collaborative and mission-driven culture focused on transforming patient outcomes.</li>
<li>Competitive executive compensation and equity participation.</li>
</ul>
 
Please apply directly here or contact me on the following details if you have any questions:
<a href="mailto:joel.isaac@vividresourcing.com" target="_blank">joel.isaac@vividresourcing.com</a>
+1 (980) 222 2267

Chief Scientific Officer

<h3>Job Description</h3>
Are you an experienced Sr Microbiologist-Steriliz with a desire to excel? If so, then Talent Software Services may have the job for you! Our client is seeking an experienced Sr Microbiologist-Steriliz to work at their company in Billerica, MA.
 
Primary Responsibilities/Accountabilities:
<ul>
<li>Responsibilities may include the following and other duties may be assigned.</li>
<li>Work relatively independently with guidance and direction from senior members of the staff and the manager.</li>
<li>Assure all Quality requirements are in compliance with regulations and product specifications</li>
<li>Provide new product development sterilization / microbiology validation support</li>
<li>Perform, coordinate, execute, and summarize all areas of sterilization validation (EtO)</li>
<li>Work with little guidance to design and validate sterilization cycles for new products including new sterilizer IQ/OQ/PQ reports, calibration, and production support.</li>
<li>Work with little guidance to develop, implement and maintain sterilization processes, certifications and procedures for the sterilization operations within Healthcare.</li>
<li>Support the development and validation of cleaning, disinfection and sterilisation of reprocessable devices</li>
<li>Support internal and external audits</li>
<li>Prepare written responses to regulatory questions</li>
<li>Review engineering change orders.</li>
<li>Resolve non conformances and implement corrective action</li>
<li>Work with Facility Maintenance and other departments for any Sterilizer, CEA, or Lab improvement/corrective activities.</li>
<li>Participate in special projects as assigned.</li>
<li>Reviews Supplier Change Control (SCC) notifications for impact to sterilization/microbial testing.</li>
<li>Assuring that the Microbiology / Sterilization function is maintained per industry standards.</li>
</ul>
 
Qualifications:
<ul>
<li>Requires advanced knowledge of job area combining breadth and depth, typically obtained through advanced education combined with experience. May have practical knowledge of project management. Requires a University Degree and minimum of 4 years of relevant experience, or advanced degree with a minimum of 2 years relevant experience.</li>
<li>Cleaning, Disinfection and Resterilization of reprocessable devices</li>
<li>Controlled Environments</li>
<li>Has ethylene oxide sterilization experience</li>
</ul>
 
Preferred:
<ul>
<li>Certified Industrial Sterilization Specialist (CISS)</li>
<li>Experience in Ethylene Oxide Sterilization validation</li>
<li>Thorough knowledge of fundamental microbiology principles, methods, and procedures, including knowledge of bacteria morphology and staining, aseptic technique specifically as they relate to sterilization methods.</li>
<li>Environmental Monitoring (EM) subject matter expertise.</li>
<li>Expertise in clean room requirements and gowning requirements</li>
<li>Ability to multi-task, skilled in planning, organizing, coordinating projects, and working independently.</li>
<li>Ability to write protocols, reports, procedures, and work instructions</li>
<li>Ability to read and interpret documents related to medical device sterilization and cleanrooms Including: International standards, regulations, technical procedures, journals, regulatory publications. Familiarity with FDA regulations.</li>
<li>Working knowledge of MS Word, Excel, PowerPoint, MS Outlook, Project</li>
<li>Expertise in cGMP's and quality systems as related to terminally sterilized medical devices.</li>
<li>Knowledge in compendial (AAMI, USP, ISO) methodologies and techniques, including: ISO 13485, 11135, 14644 (series), 14698 (series), 17665, 17664, 11737-1/-2/-3, and ANSI/AAMI ST72.</li>
</ul>

Sr Microbiologist-Steriliz

<h3>Job Description</h3>
Job Description:
The Role
We are looking to hire a Director, Quant Strategist to strengthen our US team. By combining hands-on quantitative research with team leadership, the successful candidate will be accountable for developing and monitoring strategies, ensuring model robustness, troubleshooting issues, and driving workflow enhancements.
This role will play a central part in driving our DeFi research efforts and requires a strong technical background, excellent problem-solving skills, and the ability to manage and mentor a small team whilst coordinating our team efforts across multiple stakeholders, and cross-regional teams.
Key Responsibilities
Strategy Research &amp; Implementation
<ul>
<li>Conduct research into yield-oriented strategies across of a range of market structures and venues, with an emphasis on identifying risk-adjusted return opportunities</li>
<li>Design and run backtests to evaluate strategy performance, stress-test assumptions, and establish statistical robustness</li>
<li>Help deeply analyze protocols to understand mechanics, risks, and potential drivers of yield. Translate insights into research hypotheses and strategy ideas</li>
</ul>
Monitoring &amp; Troubleshooting
<ul>
<li>Act as a first line of response for alerts, coordinating with global colleagues to escalate and resolve issues quickly</li>
<li>Translate lessons learned from monitoring into research and operational playbook improvements</li>
</ul>
Team Leadership
<ul>
<li>Manage and mentor a team of quants/analysts: run sprints, allocate tasks, and oversee objectives and results</li>
<li>Conduct code and strategy reviews, enforce testing standards, and support professional development</li>
<li>Foster a culture of collaboration, technical excellence, and delivery focus</li>
</ul>
Risk &amp; Stakeholder Interaction
<ul>
<li>Present weekly PnL, risk metrics, and performance attribution to senior management</li>
<li>Ensure transparent communication and reporting to internal stakeholders</li>
</ul>
The Expertise and Skills You Bring
Technical Expertise
<ul>
<li>Proficiency in Python (e.g., Pandas, NumPy, PyTorch, etc.) and SQL with the ability to write production-quality, maintainable code</li>
<li>Strong grounding in portfolio mathematics, risk modelling and statistical methods</li>
<li>Experience building and maintaining research infrastructure, including data pipelines, backtesting frameworks, and related tools</li>
</ul>
Communication &amp; Engagement
<ul>
<li>Able to distill complex models into actionable insights for technical and non-technical stakeholders</li>
<li>Collaborate style and effective at working across teams and time zones, fostering strong engagement with colleagues</li>
</ul>
Analytical &amp; Research Skills
<ul>
<li>Skilled at working with large, complex, and imperfect datasets, extracting signal from noise, and applying methods ranging from classical statistics to machine learning where appropriate</li>
</ul>
Professional Experience
<ul>
<li>Typically, 10+ years of relevant experience in digital assets, and/or quantitative research</li>
<li>Advanced degree (Master’s or PhD) in a quantitative field (e.g. Mathematics, Statistics, Computer Science, Physics, or a related discipline)</li>
<li>Previous experience managing or mentoring a small team of quants, developers, or researchers</li>
</ul>
Preferred Qualifications
<ul>
<li>Prior exposure to DeFi yield strategies (staking, LP, lending, re-staking)</li>
<li>Experience with systematic trading across traditional asset classes (equities, FX, commodities, fixed income etc.)</li>
<li>Demonstrated initiative in generating ideas and improving processes</li>
<li>Comfort working across time zones and collaborating with distributed teams</li>
</ul>
The Team
Fidelity Digital Assets® is dedicated to building products and services that help institutions adopt digital assets and innovate within the increasingly digital world of finance. Fidelity Investments began researching blockchain technology and digital assets solutions in 2014, and years of research and development have provided us with the deep expertise necessary to build the future of finance.
Come join the Quantitative Strategies team within Fidelity Digital Assets® to help grow our business initiatives within DeFi and contribute to our research and product capabilities using your insights.
The base salary range for this position is $126,000-255,000 USD per year.
Placement in the range will vary based on job responsibilities and scope, geographic location, candidate’s relevant experience, and other factors.
Base salary is only part of the total compensation package. Depending on the position and eligibility requirements, the offer package may also include bonus or other variable compensation. 
We offer a wide range of benefits to meet your evolving needs and help you live your best life at work and at home. These benefits include comprehensive health care coverage and emotional well-being support, market-leading retirement, generous paid time off and parental leave, charitable giving employee match program, and educational assistance including student loan repayment, tuition reimbursement, and learning resources to develop your career. Note, the application window closes when the position is filled or unposted.
Please be advised that Fidelity’s business is governed by the provisions of the Securities Exchange Act of 1934, the Investment Advisers Act of 1940, the Investment Company Act of 1940, ERISA, numerous state laws governing securities, investment and retirement-related financial activities and the rules and regulations of numerous self-regulatory organizations, including FINRA, among others. Those laws and regulations may restrict Fidelity from hiring and/or associating with individuals with certain Criminal Histories.
Most roles at Fidelity are Hybrid, requiring associates to work onsite every other week (all business days, M-F) in a Fidelity office. This does not apply to Remote or fully Onsite roles.
Certifications:Category:Data Analytics and Insights

Director, Quant Strategist

<h3>Job Description</h3>
Job Description
We are seeking a motivated and skilled Research Assistant with a strong background in molecular biology and assay development to support our research team. The ideal candidate will have hands-on experience with cell culture, protein purification, and the development of molecular assays. This role is critical in helping to drive the early-stage research that underpins our core product development and will involve working closely with a small, interdisciplinary team of scientists and researchers.
Key Responsibilities:
<ul>
<li>Conduct molecular biology experiments, including DNA/RNA extraction, PCR, cloning, and gene expression analysis.</li>
<li>Develop and optimize assays to support ongoing research projects, ensuring high sensitivity, specificity, and reproducibility.</li>
<li>Maintain and troubleshoot mammalian and/or bacterial cell cultures, following sterile techniques and ensuring cell line viability and quality.</li>
<li>Perform protein expression and purification tasks, including the use of chromatography, filtration, and centrifugation techniques.</li>
<li>Prepare buffers, reagents, and media required for assays and cell culture work.</li>
<li>Analyze experimental data, maintain accurate lab records, and present findings in team meetings.</li>
<li>Collaborate with cross-functional team members to support the design, implementation, and optimization of research protocols.</li>
<li>Contribute to lab maintenance, including ordering supplies, organizing samples, and maintaining equipment.</li>
</ul>
Qualifications:
<ul>
<li>Education: Bachelor’s or Master’s degree in Molecular Biology, Biochemistry, Biotechnology, or a related field.</li>
<li>Experience: 1-3 years of hands-on experience in a research setting, preferably within a biotech or life sciences startup.</li>
<li>Technical Skills:
<ul>
<li>Proficiency in molecular biology techniques such as PCR, qPCR, cloning, and gel electrophoresis.</li>
<li>Experience with mammalian and/or bacterial cell culture, including cell line maintenance, transfection, and viability assays.</li>
<li>Knowledge of protein purification techniques (e.g., affinity, ion-exchange, size-exclusion chromatography) and experience using related equipment (e.g., AKTA).</li>
<li>Familiarity with assay development, including ELISA, reporter assays, and fluorescence-based assays.</li>
</ul>
</li>
<li>Computer Skills: Proficient in data analysis software (e.g., Excel, GraphPad Prism) and able to use standard lab information management systems.</li>
<li>Soft Skills: Strong attention to detail, excellent organizational skills, and the ability to work both independently and in a team.</li>
</ul>

Research Assistant

<h3>Job Description</h3>
Job Description
Are you detail-oriented and passionate about maintaining high-quality standards in a fast-paced environment? We're looking for a fill-time Post Processing Technician I to join our team in the Processing Department. Available shifts include Monday through Friday 7:30AM - 4:00PM or Friday through Monday 7:00AM - 5:30PM. This position plays a vital role in supporting the post-processing process, ensuring compliance, and maintaining product quality from start to finish. If you're excited to work with a dedicated team in a dynamic setting, this could be the perfect opportunity for you!
As a Post Processing Technician I, you will be responsible for performing routine tasks across all processing areas, working under the guidance of the Processing Supervisor and Post Processing Technician III. Your responsibilities will include conducting green waste disposal processes, trimming batches by hand and machine, and assisting with the dry and cure processes. You'll play a role in maintaining quality control measures, ensuring batches meet product standards, and supporting inventory management by keeping accurate records. In addition, you will be expected to keep your workspaces and machinery clean, sanitized, and organized to maintain operational efficiency.
Previous experience is preferred but not required. The ideal candidate will have a keen eye for detail and the ability to focus on sensitive and complex tasks. Strong verbal and written communication skills, flexibility, and adaptability are essential to succeed in this role. You must be able to stand for extended periods, lift up to 50 lbs occasionally, and perform manual tasks requiring fine motor skills. Safety is a priority, and you will be required to maintain balance while using ladders or performing tasks such as stooping, kneeling, or reaching.
If you're ready to be part of a supportive team in an evolving environment and are excited about contributing to our post-processing process, we encourage you to apply today!

Post Processing Technician 1

<h3>Job Description</h3>
Job DescriptionJob Description: Senior Computational Biologist Department: Data Science, PIRC Reports to: Director of AI in Drug Development Job Summary: We are seeking a highly motivated and skilled Senior Computational Biologist to join our dynamic data science team. This individual will apply advanced OMICS-oriented analytical methods, statistical modeling, and ML/AI to accelerate discovery and decision-making in support of PIRC’s expanding research programs. The ideal candidate will leverage their deep expertise in computational biology, deep learning, and data-driven drug discovery to develop state-of-art solutions. This role involves close, cross-functional collaboration with Immunology, Translational Science, and Biologics teams to build sophisticated algorithms and predictive models that drive our pipeline. The Company: It’s not often you get the chance to make a real impact on the lives of others, while expanding your own possibilities. You’ll find that rare opportunity at PharmaEssentia. Join us, and let’s transform lives, together. PharmaEssentia Corporation is a rapidly growing biopharmaceutical innovator. We are leveraging deep expertise and proven scientific principles to deliver effective new biologics for challenging diseases in the areas of hematology and oncology, with one approved product and a diversifying pipeline. We believe in the potential to improve both health and quality of life for patients with limited options today through the combination of rigorous research and innovative thinking. Founded in 2003 by a team of Taiwanese-American executives and renowned scientists from U.S. biotechnology and pharmaceutical companies, today we are listed on the Taipei Exchange (TPEx: 6446) and are expanding our global presence with operations in the U.S., Japan, China and Korea, along with a world-class biologics production facility in Taichung.&nbsp; This role will be in the PharmaEssentia Innovation Research Center (PIRC), the US R&amp;D center for PharmaEssentia. As PIRC is essentially in startup mode with the full backing of PharmaEssentia HQ, this is an exciting time for PIRC and the Data Scientist will have great influence in developing and growing PIRC from the ground floor up. Key Responsibilities
<ul>
<li>Lead multi-omics data analysis across diverse datasets, including genomics, bulk and single-cell transcriptomics, proteomics, metabolomics and pathway analysis, to address critical questions in target identification, prioritization, and translational science</li>
<li>Design and implement novel computational modules and frameworks to enable seamless integration and interpretation of multi-omics data, driving insights for R&amp;D</li>
<li>Develop and apply machine learning and AI algorithms to uncover patterns and generate predictions from complex biological datasets, and accelerate target discovery and validation efforts</li>
<li>Enhance internal cross-disciplinary collaboration with project teams to align computational strategies with project goals and ensure robust biological interpretation of data</li>
<li>Establish best practices for data management, quality control, and reproducibility in bioinformatics pipelines, and create intuitive visualizations and detail-oriented reports to communicate findings with stakeholders, enabling data-driven decision-making&nbsp;</li>
<li>Continuously evaluate and adopt cutting-edge computational tools, algorithms and technologies to stay at the forefront of the field and enhance data analysis capabilities</li>
<li>Contribute to the strategic planning of computational/AI initiatives, influencing the direction of research programs and technological investments</li>
<li>Contribute to scientific publications, conference presentations, showcasing advancements in bioinformatics and AI, and their impact on drug discovery and translational research</li>
</ul>
 Qualifications
<ul>
<li>Ph.D. in Bioinformatics, Computational Biology, Computer Science or relevant quantitative discipline</li>
<li>At least 3-years work experience in combining bioinformatics/computational biology analysis and cutting-edge computational approaches (including ML/AI) for project support in cross-functional biotech or pharma setting.&nbsp;</li>
<li>Expertise in multi-omics data analysis and result interpretation (genomics, transcriptomics and scRNASeq are must, spatial omics and image are plus)</li>
<li>Proficiency in Python and R, familiarity with database management</li>
<li>A strong understanding of the drug discovery and development, including target identification, lead optimization, translational research, and early clinical development</li>
<li>Experience in a therapeutic area relevant to oncology and immunology</li>
<li>Working knowledge of traditional machine learning algorithms, Deep learning frameworks and LLM, and their applications in drug discovery</li>
</ul>
 EEO Statement: At PharmaEssentia Innovation Research Center (PIRC), we are committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants without regard to race, color, religion, sex, pregnancy (including childbirth and related medical conditions), national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information (including characteristics and testing), military and veteran status, and any other characteristic protected by applicable law. PIRC believes that diversity and inclusion among our team are critical to our success as a global company, and we seek to recruit, develop and retain the most talented people from a diverse candidate pool.&nbsp; PIRC does not accept unsolicited agency resumes. Staffing agencies should not send resumes to our HR team or to any PIRC employees. PIRC is not responsible for any fees related to unsolicited resumes from staffing agencies. &nbsp;
At PharmaEssentia, our goal is to treat as many people with cancer as possible. That means challenging the status quo with better science that leads to better lives. By joining our team, you will not only expand your own possibilities, but you will contribute to expanding options for people with cancer.
<a href="https://us.pharmaessentia.com/careers/" target="_blank">https://us.pharmaessentia.com/careers/</a>
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